How do you identify something no one has a test for? Designer drugs replicate the effects of known, illicit drugs but evade ...

Some new drugs replicate the effects of known illicit substances, but can't presently be identified in urine samples as there ...

Indole, a molecule made up of a six-membered benzene ring fused to a five-membered ring containing nitrogen, forms the core ...

Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and ...

Hunting for drugs in chemical space As more chemicals are available to test in the search for drugs, researchers have to decide where to look ...

The FDA and EMA require CNS penetrant drug candidates to be assessed for abuse potential. As part of this assessment, the chemical similarity to known drugs of abuse is analyzed. Scitegrity ...

Southwest Research Institute scientists and engineers have developed a custom large language model (LLM) to accelerate drug ...