Heliot Ramos, Rafael Devers and Wilmer Flores homered off Nestor Cortes in the first inning and the San Francisco Giants beat San Diego 4-3 to hand the Padres their fourth straight loss.

Gavin Sheets hit two of San Diego's four home runs and drove in four runs, and Fernando Tatis Jr. robbed San Francisco's Rafael Devers of a homer as the Padres beat the Giants 8-1 on Wednesday night.

These two weeks in which the Padres are playing only the Giants and Dodgers have provided some mood swings. The Padres moved into first place in the National League West with a sweep in San Francisco last week and fell back into second place when they were swept in Los Angeles over the weekend.