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Download and install python 3.8+, perhaps from www.python.org but probably from conda. Preload binary packages from conda (or your system package manager): numpy, scipy, matplotlib, h5py, pillow, ...
These include many general-purpose packages such as regex, PyYAML, and cryptography, and scientific Python packages including NumPy, pandas, SciPy, Matplotlib, and scikit-learn. Pyodide comes with a ...