The heart is a highly sex-biased organ, as sex shapes innumerable aspects of heart health and disease. Sex chromosomes and sex hormones —testosterone, progesterone, and estrogen— establish and ...
Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells. Mitochondria-encoded circular RNAs (mecciRNAs) are attracting more attention, and several members of ...
Temerty Faculty of Medicine, University of Toronto, Canada. (K.G.) Women’s College Hospital, Toronto, Canada (K.G., H.A.-Q.). ICES (formerly known as the Institute ...
A 78-year-old male with a past medical history of aortic stenosis, atrial fibrillation, hyperlipidemia, heart failure with preserved ejection fraction, obstructive sleep apnea, obesity, and chronic ...
Machine learning (ML) models are algorithms that derive insights from data to automatically generate predictions or decisions without being explicitly programmed. ML algorithms are broadly categorized ...
The activation and polarization of T cells play a crucial role in atherosclerosis and dictate athero-inflammation. The epigenetic enzyme EZH2 (enhancer of zeste homolog 2) mediates the H3K27me3 ...
Chronic kidney disease (CKD) has emerged as a significant risk factor that accelerates atherosclerosis, decreases muscle function, and increases the risk of amputation or death in patients with ...
Department of Cell Biology, Duke University School of Medicine, Durham, NC. (R.M.P., A.P.L.) Division of Pediatric Cardiology, Department of Pediatrics, Duke ...
Suboptimal vascular risk factor screening after pregnancy-related hypertension or diabetes is a missed opportunity for cardiovascular prevention. Multifaceted strategies to improve screening, ...
Hypertension in pregnancy contributes substantially to maternal morbidity and mortality, persistent hypertension, and rehospitalization. Hypertensive disorders of pregnancy are also associated with a ...
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