Tobirama died during the First Great Ninja War protecting Konoha's future.

Tobirama's techniques and abilities are all centered around countering the Uchiha, reflecting his skepticism for the clan.

According to this Naruto theory Tobirama may have created his S-rank jutsu to immortalize Hashirama for the fear of Uchiha ...

Kabuto sought power, and his search led him to various abilities, including a perfected reanimation jutsu. Before Kabuto, Tobirama and Orochimaru had practiced this form of necromancy; however, ...